Hi Majda,
that's an intriguing case of new brain constellations which I would like to ask some questions to clearly understand:
*the onset of the depression and the osteoarthritis almost coincide (20/21 years ago). Was it then that her mother and/or her brother had died?
The manic and depressive episodes would tell me that this incident was impacting the second hemisphere, and from then on the scale is swinging.
The first territorial conflict was the forced marriage against her will. Then there were several other conflicts - the boundary breach by her mother-in-law, the infidelity (of her second husband?), but her brother had been her faithful resource. His death weighed heaviest, and this was a shock-fright - a "female type conflict", yet causing depression, which means the conflict weight is more on the right brain side. 
You see here what I discussed in our previous class - that these male and female themes can apply for both hemispheres.

*When she gets manic, how is that expressed - what is she manic about?
It may be possible that her chronic self-devaluation is related to that...

Obviously, the abandonment syndrome belongs to her pattern, as she suffered the loss of her main resource - her brother, and never got over this.
So, in order to heal, the first thing must be to address that. She found a very good META-meaning: “I mourn and I accept my grief, life goes on and I enjoy the present”. I'm sure she can need help to achieve this, and tapping will be a good start!
The other META-meaning “I deserve happiness, love and respect” is true for allowing herself to overcome self-devaluation. At the same time, it seems to be dependent on that others show her this love and respect, which may or may not be the case. In my view, she wants to love and respect herself and her history first, it's easier for others to follow! It also might make her feel less obedient and more self-sufficient.
Would you agree?