!Myelin Sheath of Nerves
!!Anatomy
Each peripheral nerve is covered externally by a dense sheath of ((Musculoskeletal - Connective Tissue|connective tissue))  the epineurium. Underlying this is a layer of flat cells forming a complete sleeve  the perineurium. Perineurial septa extend into the nerve and subdivide it into several bundles of fibres. Surrounding each such fibre is the endoneurial sheath. This forms an unbroken tube which extends from the surface of the spinal cord to the level at which the axon synapses with its muscle fibres or ends in sensory receptors. The endoneurial sheath consists of an inner sleeve of material called the glycocalyx and an outer  delicate  meshwork of collagen fibres. Peripheral nerves are richly supplied with blood. 

The myelin sheath is an __electrically-insulating phospholipid layer__ that surrounds the axons of many neurons in the central and autonomic nerve systems. It runs in spirals around the axon, interrupted by Ranvier nodes. By saltatoric conduction from node to node, __speed of transmission__ is enhanced. In the central nervous system, myelination happens through oligodendrocytes, in the peripheral nerves through Swann-cells. Both of these are glia cells.

{img fileId="103" thumb="box"}graphic: wikipedia

!!Brain
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{img fileId="348" thumb="box"} Cerebellum areas, graphic: [https://www.slideshare.net/HarshshaH103/cerebellum-its-function-and-releveance-in-psychiatry|Harsh shaH medical instructor]

!!!Relay
__Cerebellum __( + / - ) dorsal left & right
{img fileId="174" thumb="box"}

!!Mind
!!!Theme
Fear for touch, pain sensation (conduction and evaluation)

!!!Emotions and Thoughts
__Fear, resistance__
Touch is experienced as threatening when coupled to stored painful experiences (blow, accident, trauma) Can also be connected to a strong pain from the ((Musculoskeletal - Periosteum (Visceral Fascia)|periosteum)).

*Leave me!
*This hurts!
*I don't want that!
*I don't like to be touched.
*I have to block that off!

!!!META-Meaning
*I love to touch and be touched carefully. 
*Now I can allow myself to feel and be secure.
*I am well-protected!

!!Organ
!!!Stress Phase Symptoms
Enhanced activity and __proliferation in the glia cells__ which can concern several layers of ((Integumentary - Skin Overview|skin)) and ((Musculoskeletal - Connective Tissue|connective tissue)) and be diagnosed as neurofibroma, Schwannoma, peripheral glioma or fibroma. The sensory stimulation (deep sensitivity of the cerebellum) is peripherally perceived as normal but it is not transmitted. It means that the perception is ‘absorbed’ by the neurofibroma: pain is as reduced as sensitivity, but total __loss of sensation__ (anesthesia) is also possible. Possibly the cerebellum constellation plays a major role here.

An inherited pattern with neurofibroma and pigment changes is Morbus Recklinghausen. 

!!!Regeneration Phase Symptoms
Neurofibromas can remain, or be degraded in presence of microbes (fungi, mycobacteria), in which case a __sebaceous cyst__ appears (atheroma) Sensitivity is restored immediately after the conflict resolution, possibly resulting in temporary hypersensitivity. 

In chronic processes or sensitization, the myelin sheath can be degraded which leads to __impairment of impulse conduction__ in the affected nerves. Typical syndrome is multiple sclerosis, here often both ((Nervous - Motoric Innervation|motoric)) and ((Nervous - Sensory Innervation|sensory)) qualities are affected and lead to ((Musculoskeletal - Skeletal Muscles|muscular)) atrophy as a consequence of self-devaluation.. 

__Possible diagnoses__: disseminating encephalomyelitis (ADEM), motoric axonal neuropathy, Baló sclerosis, chronic inflammatory demyelinating polyneuropathy, Guillain-Barré syndrome, funicular myelosis, Miller-Fisher syndrome, transverse myelitis. 

!!!Biological Meaning
The enhanced insulation and desensitiation is meant to neutralize the perception of pain.

!!Social
!!!Examples
*A 7 y o girl has to leave her playmates because her family moves to another country. She suffers a motoric and a pain conflict as well as abandonment, and develops progressive MS. 
*A woman with emotional background of violation (contact- pain-, defilement- and sexual conflicts) successively gets neurofibromas over big parts of her body. (Klapp)
*An athlete who gets the diagnosis MS feels devastated. The generally reversible process of self-devaluation and muscle weakening gets chronic by her own associations, values and thoughts and she experiences progressive weakness. Through perseverant transformation of emotions and beliefs accompanied by individual training, she rebuilds her strength. (Valentic)
*A young woman bears unconscious guilt and beliefs that she is "bad" by birth. She learns a healing profession to counterbalance the inner conflict. She successively develops MS with motoric and sensory paralysis. Through spirituality she finds her inner solution, and with patience and training she regains her capabilities and finds her identity.(Kujama) 

!!Additional Information
Neurofibromas are divided into 2 categories: dermal and plexiform. Dermal neurofibromas are connected to one single peripheral nerve, while plexiforme neurofibromaas are associated to several nerve bundles. Dermal neurofibromas appear mostly in the beginning of puberty. They can cause stinging, itch, pain and deformity. 

__Fibromyalgia__ is possibly connected to demyelinization of nerves. [http://www.examiner.com/article/could-fibromyalgia-have-autoimmune-demyelinating-cases|http://www.examiner.com/article/could-fibromyalgia-have-autoimmune-demyelinating-cases]

!!!Constellations
__Cerebellum Constellation__: physical & emotional desensitization in vulnerability concerning both hemispheres, "Emotional burnout"

!!!Differential Diagnosis
__Fibromyalgia__ (which is usually a combination of several skin and/or bone processes)

__Skin-((Integumentary - Skin - Epidermis|Epidermis))__ (Cerebral Cortex -/+): hypesthesia and dry, pale skin in stress phase (contact - distance)

__Skin-((Integumentary - Skin - Dermis (Leather Skin)|Dermis))__ (Cerebellum +/-): overfunction of sebacious glands in stress phase (vulnerability), fatty skin, melanoma; regeneration phase: abscess, acne, skin tuberculosis, leper

__((Musculoskeletal - Periosteum (Visceral Fascia)|Periosteum)) - Bone sensitivity__ (Cerebral Cortex -/+): hypersensitivity, strong pain in stress phase (indignating pain)

__((Nervous - Sensory Innervation|Sensory Innervation))__ (Cerebral Cortex -/+): Stress phase (feeling inhibited): anesthesia, numbness; regeneration phase: paresthesia, itch, tingling sensations

__((Nervous - Motoric Innervation|Motoric Innervation))__ (Cerebral Cortex -/+): Stress phase (action inhibited): paralysis

